BEACON Researchers at Work: Evolving Virtual Creatures

This week’s BEACON Researchers at Work post is by University of Texas graduate student Dan Lessin and Nicole Lessin.

helicopterAs an undergraduate in the 1990s, I was studying studio art, animation, and computer graphics at Harvard when I first came across a video that accompanied what we now know to be a landmark publication by Karl Sims. This work demonstrated evolved virtual creatures made of simple cube-like shapes performing lifelike behaviors in a physically simulated environment. Sims had simultaneously evolved the bodies and brains of these creatures to perform locomotion on land and through water, as well as a number of other behaviors. Some of them hopped, some pulled themselves along the ground, others paddled or snaked through the water, and the most compelling examples were even able to follow and navigate to a user-controlled light source. It was like spying on alien life forms inhabiting a new world. And they all looked different from one another, as each had its own body plan and style of motion which had emerged naturally from Sims’ process of simulated evolution.

Like others who have seen Sims’ work, I found these creatures extremely compelling. I would later learn that my reaction was an example of an effect called “perceptual animacy,” the phenomenon through which viewers attribute internal motivations and desires to even the simplest of geometric shapes if they display the right kind of movement. Maybe bringing even more behavioral complexity to these virtual creatures could elicit an even stronger response of this type.

Evolved virtual creatureWhen I returned to academia after many years to begin work on a PhD in Computer Science at the University of Texas at Austin, I was pleasantly surprised to find that, despite many extensions to Sims’ work in a number of different fields, nobody had yet demonstrated more complex behaviors than the light following that Sims had produced so many years earlier. So for my own research, I began to think about how to evolve creatures with more complex behaviors toward the end of generating even more compelling virtual creature content, such as one might find in a nature documentary or an internet cat video. For example, instead of just drifting smoothly to a target as in Sims’ work, new creatures might first move to, then strike at a target, then perhaps run away if scared, or instead maybe patiently stalk a target then pounce on it, as a real animal might do.

In contrast to Sims’ creatures, who learned their light following as one integrated skill, I set about adding behavioral complexity to my own through the use of a novel syllabus method, which was based on my time as an aviation instructor and the building-block method of instruction we employed to teach some of the more complex aspects of flying. For example, learning to hover in a helicopter is a complicated maneuver that requires the knowledge and integration of a number of different skills–using the collective to move up and down, the cyclic to move laterally, and the pedals to control heading–each of which is a challenge to master individually, let alone in combination with the others. So students are only allowed to have control over one of these elements at a time, until each is mastered on its own. Then they can learn to combine them with relative ease, resulting in a steady learning progression to achieve what might otherwise be an impossibly complex task.

instructions that make up the creature's brainApplying this kind of approach to evolved virtual creatures, I train them through a sequence of relatively simple subtasks in which the earlier skills make the later ones easier to achieve, and each task is only about as difficult as what would typically be required in a normal evolved virtual creature system. Using this method, I have so far been able to match, then approximately double the upper limit of behavioral complexity for evolved virtual creatures that had persisted for almost two decades since Karl Sims first set it in his 1994 publication. These results were presented at this year’s GECCO conference and are summarized in a 5-minute video available online [4]. The process is analogous to using a ladder rather than trying to improve your ability to jump. Through practice and the use of new techniques, you might eventually be able to jump twice as high as you can today. But if you can use a ladder, you can reach arbitrary heights with only a limited amount of effort at each step.

For more information about Dan’s work, you can contact him at dlessin at cs dot utexas dot edu.

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BEACON's Kalyanmoy Deb receives honorary doctorate

Kalyanmoy Deb receiving honorary doctorateKalyanmoy Deb, a BEACON Researcher and the Koenig Endowed Chair of Electrical and Computer Engineering at Michigan State University, received an Honorary Doctoral Degree from the Faculty of Information Technology at the University of Jyvaskyla in Finland on August 24, 2013. Prof. Deb received this recognition along with 14 other honorary degree recipients, including the President of Finland, Mr. Sauli Niinisto (Sport and Health Sciences) and three other professors from the USA: Prof. Kristine Munoz from the University of Iowa (Humanities), Prof. Thomas McKenzie, San Diego State University (Sports and Health Sciences) and Prof. Michael Lambert, Brigham Young University (Social Sciences).

The University of Jyvaskyla organizes the degree ceremony once every five years. The ceremony this year was special, as it marked the 150-year jubilee of the University of Jyvaskyla. The ceremony lasted for two and a half days, with a very formal ceremony mostly spoken in Latin, and followed a 350-year old conferment tradition, a walk-in procession from Jyvaskyla city center to a local church, a gala dinner with traditional folk dancing, and ended with a boat ride on a bright sunny day to an island for traditional Finnish food and music. During the ceremony, 179 PhD students and 230 master’s degree students received their respective degrees.

ceremony

Prof. Deb has had a long-term association with the University of Jyvaskyla since 1999. He collaborates with the Faculty of Information Technology on various projects in the area of multi-criterion optimization and decision making, delivering short courses to their international summer school courses, and co-supervising PhD students.

More about Prof. Deb’s research interests can be found at http://www.egr.msu.edu/~kdeb. Prof. Deb and BEACON Director Erik Goodman won the prestigious Wiley Practice Prize (with Oliver Chikumbo of New Zealand) from the International Society on Multi-Criterion Decision Making in June 2013.

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BEACON Researchers at Work: Survival of the Rarest

This week’s BEACON Researchers at Work blog post is by MSU postdoc Noah Ribeck.

Noah RibeckWe are all taught the basic tenet of evolution by natural selection: occasionally an individual is born with a mutation that improves its chances of having more offspring. Anyone descended from this individual will then inherit this beneficial mutation, and so over generations, that mutation has a good chance of taking over the population.

But when does evolution not quite work this way? Sometimes, the benefit of a mutation changes as it becomes more abundant in the population – this is called frequency-dependent selection. A classic example of this is Batesian mimicry, where “warning” systems of poisonous organisms (like distinctive coloration) are copied by non-poisonous species to gain the benefit of being left alone by predators. This strategy only works if relatively few are doing it: if there are too many mimics around, predators would learn not to be fooled by the tricky tactic.

In the lab, I study frequency-dependent selection in the Long-Term Evolution Experiment (LTEE), a set of 12 populations of E. coli that have been evolving in the lab of Richard Lenski for more than 58,000 generations. As you might imagine, there is nothing like Batesian mimicry here, but there is a relatively common mechanism of frequency dependence in microbes, called cross-feeding. This happens when one group feeds off a metabolic byproduct of another group. The cross-feeding group, then, only has an advantage when the group it’s feeding off is abundant. In other words, a mutation that confers the cross-feeding ability is advantageous only when rare. When this happens, the two groups can coexist in perfect harmony at an equilibrium ratio where each strategy works equally well.

The LTEE was started in 1988 with the purpose of being as simple as possible. There is only a single resource in the media (glucose) to prevent individuals from specializing on different energy sources. And to discourage cross-feeding, glucose is provided only at a low concentration to prevent a lot of buildup of metabolic byproducts. In other words, the LTEE was designed for E. coli to get better at using glucose, period.

And for the most part, that’s exactly what’s happened. But over the years, members of the lab have stumbled across a few different instances of long-term coexistence of multiple subpopulations – and in one case very long-term. One of the populations consists of two distinct subgroups that have been coexisting since around ~6,500 generations, just a few years into the experiment. They are affectionately called the “smalls” and “larges,” because the two groups were made obvious by the differently sized colonies they made on agar plates. We’ve also recently found an example of frequency dependence in another population, by looking at DNA sequence data of that population over time. In this case though, the coexistence of the two groups lasted only a few thousand generations.

To begin to study these examples, I’ve measured the competitive fitness (that is, a relative measure of reproduction speed) of the two groups against each other, at various different initial ratios. From this data, we expect to see that each group has an advantage (fitness>1) when rare, and a disadvantage (fitness<1) when common. And that’s exactly what happens: 

graphs

Measuring frequency-dependent fitness is a bit tricky, because we do it by measuring how fast one group grows while competing directly against the other. But when fitness is frequency-dependent, the fitness we’re trying to measure is continuously changing while we’re measuring it. We can account for this with the proper math, but that’s why the data you’re seeing here are smooth curves instead of data points.

To interpret this, we need to have some idea of what the frequency-dependence curve would look like for an actual cross-feeding interaction. To do that, we can model the ecology between the two groups mathematically, and compare that to our data. When we do that, the theoretical fitness a lot like a straight line, decreasing with frequency, very much like our recently discovered shorter coexistence: 

graph

But the long-term coexistence (the smalls and larges) has a bit of a twist: their frequency-dependent fitness levels off a bit at when the smalls are common. So what’s going on with the smalls? Well, we actually already know that there’s something else happening there: when the smalls are common, they start to selectively kill off the larges! This means that the fitness of the smalls (relative to the larges) gets a boost when the smalls are abundant – in other words, the smalls have an added advantage when common. This flavor of frequency dependence is not sustainable on its own: if the benefit of a mutation gets bigger as it grows in frequency, it will simply drive the other group extinct. It’s only possible for this interaction to exist indefinitely because it’s paired with an offsetting disadvantage when common, most likely from cross-feeding. 

I’m interested in the fundamental role of these ecological interactions in adaptation. Since frequency-dependent selection seems to be relatively common (even in an environment that was designed to avoid it!), can we rewrite some of the basic theories in population genetics to account for it? Do these ecologies serve to sustain genetic variance in populations to help them adapt faster? Do they serve as stepping stones to more highly beneficial genotypes that would have never been otherwise possible? Stay tuned as we work on these questions …

For more information about Noah’s work, you can contact him at ribeck at msu dot edu.

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The sweet smell of (reproductive) success

BEACON Managing Director Danielle Whittaker has published a new study demonstrating that birds may use scent to determine the quality of potential mates. From the MSU press release:

Danielle Whittaker sampling junco preen oilFor most animals, scent is the instant messenger of choice for quickly exchanging personal profiles. Scientists, however, have long dismissed birds as odor-eschewing Luddites that don’t take advantage of scent-based communications.

In a first-of-its-kind study, however, a Michigan State University researcher has demonstrated that birds do indeed communicate via scents, and that odor reliably predicts their reproductive success. The study appears in the current issue of Animal Behaviour and focuses on volatile compounds in avian preen secretions.

Birds’ preen glands are located near their tails. Using their beaks, birds extract oil from the glands and rub it on their feathers and legs. Historically, this activity was thought to simply bolster the strength of feathers. Danielle Whittaker, managing director of MSU’s BEACON Center for the Study of Evolution in Action, and her research team, however, have shown that it plays a key role in signaling reproductive health.

Photo by Nicole Gerlach

Photo by Nicole Gerlach

“This study shows a strong connection between the way birds smell near the beginning of the breeding season – when birds are choosing mates – and their reproductive success for the entire season,” she said. “Simply put, males that smell more ‘male-like’ and females that smell more ‘female-like’ have higher genetic reproductive success.”

The long-held assumption was that birds’ preferred methods of communication and mate selection were visual and acoustic cues. Studying dark-eyed juncos, Whittaker’s team compared which were more effective – chemical signals or size and attractive plumage.

The results showed that individual bird odor correlated with reproduction success while size and plumage were less reliable. The study also revealed that females were making multiple decisions based on how their potential mates smelled.

“Based on odor, females seemed to be not only choosing with which males to mate, but many times they also were selecting different males to raise their nestlings,” Whittaker said. “Interestingly enough, the cuckolding males had higher levels of a ‘female-like’ odor.”

In addition, the researchers believe odors serve as beacons for hormone levels, current condition and overall health, and genetic background.

The paper will appear in the October issue of the journal Animal Behaviour and is featured in that issue’s editorial

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BEACON Researchers at Work: Carving your academic niche via interdisciplinary research

This week’s BEACON Researchers at Work blog post is by MSU graduate student Amy Lark.

What’s the best way to fit a square peg into a round hole? We can muscle that peg via brute force into a space that doesn’t want or isn’t equipped to accommodate it, leaving both peg and hole resentfully smarting from friction burns. Or we can whittle away the pointy bits, essentially stripping away part of the peg’s identity for the sake of fitting in. Neither of these methods is quite satisfactory: both require a significant amount of time and energy, and while we might eventually be able to get it in the hole, that poor peg may never achieve a sense of belonging.

If we really care about what is best for the peg (and we should), we realize that we have been asking the wrong question. The only reasonable solution is to find a different hole, one that is large or flexible enough to be accommodating, and one that doesn’t require the peg to give up parts of itself. Sometimes these holes are prefabricated, and the challenge is simply finding one. Other times there are no suitable holes to be had, and a new one must be created. While this can be hard work, the result is a snugger fit—and a happier, more fulfilled peg.

Amy Lark

Chances are that if, like me, your interests span multiple disciplines you understand better than most the plight of the square peg. When I came to MSU as a doctoral student in Zoology many years ago, I found myself trying very hard to fit into a decidedly circular hole. For more than four years I tried to squish myself into that space, and while I enjoyed my classes and colleagues and research (studying phenotypic plasticity in cannibalistic salamanders!), I knew that the fit wasn’t great. I love biology, but also care deeply about science education and outreach. I remember a conversation I had with a committee member who said that I could only expect to do two of the three well. I didn’t feel that the science alone was fulfilling enough for me to sustain a career. Needing to follow my bliss, I spent several months looking for a space that was better suited to my interests and aspirations.

I began a new PhD program in Science Education, which was, as far as holes go, roughly the right size and shape, though it wasn’t perfect. I’ve had to do a bit of carving to create a niche that feels just right, and this happens to be at the place where science, philosophy of science, and science education overlap: 

VennMy new academic home has provided the flexibility for me to shape my doctoral program in a way that combines all of my research interests.

 After several years of teaching in Science Education and working on a number of different education research projects, I had the good fortune to become involved with the Avida-ED project, under the purview of BEACON. Avida-ED is educational software that was designed to simultaneously teach students about evolution and the nature of science. It is a simplified version of the Avida research platform for use in classrooms. It features a user interface that allows students to witness evolution in action and engage in authentic science practices. Students use Avida-ED to ask questions and develop hypotheses, design experiments to test those hypotheses, collect and analyze data, and share findings with peers. Using digital model organisms in the classroom offers many advantages over traditional biological model organisms such as Drosophila and E. coli. Avidians do not require material resources, and they evolve much more quickly, making it very easy to see evolution happening and providing large amounts of data in a single class period.

Avida populationFor my graduate assistantship with BEACON, I work with the Avida-ED curriculum development team to create lesson materials for use with Avida-ED. Our goal is to develop materials that reflect evidence-based best teaching practices and that are aligned with national science education standards and reform recommendations. We know from discipline-based education research (DBER) that students learn about science best when content is integrated with the practices of science. Therefore, every Avida-ED exercise not only targets fundamental evolutionary concepts, but simultaneously also engages students in authentic science practices. We try to link each lesson to biological examples so that students can see the same patterns occurring in both digital and biological populations. An example is the lesson I developed on the effects of mutation rates on individual organisms. This exercise allows students to use digital organisms to test claims made by researchers who studied butterflies that had been exposed to radiation from the damaged Fukushima Daiichi Nuclear Power Plant complex in the aftermath of the Great Japan Earthquake of 2011 (Hiyama et al., 2012). Students use Avida-ED to reproduce the pattern found in the case study and independently support the researchers’ findings.

Avida organismsFor my dissertation I am investigating how biology instructors use Avida-ED in their classrooms and assessing student learning outcomes. My study includes ten courses from eight institutions across the United States. The study cases range from an AP biology class at a private Catholic high school to an introductory honors biology course for non-majors to an upper-division evolution course at a very large public research university. My goal is to look for patterns across these very different contexts to see if, despite the variability, there are commonalities that might be attributed to Avida-ED. One pattern that I have found is that in lower-division courses (e.g., introductory biology) student understanding of fundamental evolutionary concepts—such as the origin of genetic diversity and the basic elements of Darwinian natural selection—increases significantly after engagement in lessons with Avida-ED. Student acceptance of evolution as a real phenomenon that explains the diversity of life on earth and that is based on scientific evidence also increases significantly. What’s more, there is a significant, positive relationship between the change in both understanding of and acceptance in evolution from pre- to post-test, suggesting that the more students can observe and test evolutionary processes in action, the more they accept evolution as true (or vice versa). These preliminary results are promising and add support to the growing body of evidence showing that integrating content and practices is one of the most effective ways to teach science.

Reuleaux triangleI wouldn’t be where I am today had I not cho

sen to eschew sacrificing the things I care about, to refuse cutting away my passion for education and outreach in order to fit within the sciences. I am very thankful to my PhD program and to BEACON for having provided the opportunity and support to conduct this exciting research that lies at the nexus of science, philosophy of science, and science education. But I suppose it isn’t really accurate to say that I am a square peg after all. The shape made by the three intersecting circles of the Venn diagram is known as a Reuleaux triangle. One of the neat things about this particular shape is that if you use it as a drill bit, you can actually bore square holes. In my case, being interdisciplinary has been a great way to create a niche accommodating of my Reuleauxian nature. BEACON holds interdisciplinary research as central to its mission, and is a fantastic home for someone with such overlapping interests. It provides a comfortable space for researchers to combine their passions in unique and innovative ways, and to feel a sense of fulfillment and belonging.

Hiyama, A., Nohara, C., Kinjo, S., Taira, W., Gima, S., Tanahara, A., & Otaki, J. M. (2012). The biological impacts of the Fukushima nuclear accident on the pale grass blue butterfly. Scientific Reports, 2(570). Retrieved from  doi:10.1038/srep00570

For more information about Amy’s work, you can contact her at majchrz1 at msu dot edu.

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What's in a (mutation's) name?

Cross-posted from UT postdoc Art Covert’s blog, Covert Science(ish)

Names are generally very arbitrary things. In the words of The Bard: “A rose by any other name would smell as sweet.” This may be true for roses, but for mutations, names carry a great deal of meaning. Beneficial mutations are good, they improve an organism’s chances for survival (i.e. raise its fitness). Deleterious mutations are bad, they reduce an organisms chances for survival (lower fitness). One type of mutation is distinctly sweet, the other distinctly wretched.

Mutations are assigned their names when they first appear in a population. A mutation that improves fitness is assumed to be good and a mutation that lowers fitness are assumed to be bad. These name assignments seem nice and neat and simple, but they are predicated on the assumption that a mutation’s fate is unalterable. Good mutations are kept, bad mutations are purged by selection, very neat and tidy just as we scientists prefer it.

The picture becomes murkier when you allow for a second mutation that appears on the same genome as the first. That second mutation has the potential to alter the effect of the first. Good mutations may become bad and bad mutations become good (Figure 1).

Figure 1: An example of the two mutation system described above (From Covert et al 2013). Both mutations A and B individually are deleterious, but A and B together are extremely beneficial.

Figure 1: An example of the two mutation system described above (From Covert et al 2013). Both mutations A and B individually are deleterious, but A and B together are extremely beneficial.

So if a second mutation can alter the effect of the first then all bets are off, right? Classical evolutionary theory doesn’t think so, and has held that such infrequent occurrences are probably unimportant. Mutations are rare; getting two mutations is even rarer. Getting the right two mutations, close together, to not only ameliorate a deleterious mutation, but to actually open up new beneficial mutations that weren’t accessible before? Pishaw! You get better odds at the blackjack table! So the literature generally holds that bad mutations stay bad, and good mutations stay good, and that’s how it’s been in evolutionary theory for a long time.

Evolution isn’t about playing one hand of blackjack though, its about playing lots and lots of hands, over a very long period of time. On a long enough timescale, you will eventually see one of these rare chance events. Deleterious mutations are extremely common, a genotype with a deleterious mutation will persist in the population for a few generations before it’s purged. In that short time, if one of that genotype’s progeny acquires a second mutation their is a small chance that the two mutations together will actually be good. There is also a possibility that in addition to ameliorating the deleterious effect, the pair of mutations also pushes the population’s genotypes closer to other beneficial mutations. These super-compensatory mutations are rare, but have a huge impact when they finally emerge.

The question is not “if” or “when”, but of how important these super-compensatory mutations are. Until now this question has been open, but now my colleagues and I have begun to shed light on it. Using self-replicating computer programs (digital organisms) we examine the effects of deleterious mutations in two ways that are not possible with organic study systems.

In our first set of experiments, we replace all deleterious mutations with beneficial or neutral mutations making it impossible for deleterious mutations to appear at all. In contrast, mutations in the population normally occur completely at random with the vast majority of them having deleterious or lethal fitness effects. Surprisingly, when we compare the no-deleterious populations to normal populations we find that the normal populations have much much higher fitness. So, at least some immediately deleterious mutations in the long run are creating a net benefit. But is it all deleterious mutations that are important or just a few?

With our second set of experiments we undid every instance of a deleterious mutation on the lineage from the starting organism to the most successful genotype in each population. Undoing these mutations asks the question “what would have happened without this one mutation?” Throughout all of the populations with deleterious mutations we found rare instances of super-compensatory deleterious mutations, which also lead populations to previously inaccessible beneficial mutations. In other words, occasional steps that are not immediately beneficial may lead to huge rebounds.

This isolation of historically significant super-compensatory mutations is what sets our work apart from other works on the role of deleterious mutations. We actually identify which deleterious mutations are leading to higher fitness in the long run and we measure their impact on the long-term evolution of the population.

The most startling thing we found when we looked at individual super-compensatory mutations, is that they occur in minuscule quantities. Out of 50 replicate populations, each experiencing 45,000 generations of evolution, we found only 36 super-compensatory mutations. Of those 36, only 11 were found to be necessary for the populations’ continued evolution. But theses 11 super-compensatory mutations fundamentally altered the outcome of evolution. Without these extremely rare events the evolutionary process stalls out, possibly for very long periods of time.

So the story is not told by the name alone. Every once in a while, a deleterious mutation will interact with other mutations in a way that makes them more beneficial together; interactions such as these are known in the literature as “epistatic” mutations. These rare, but historic events are pathways to essential variation in evolving populations that may become evolutionarily stuck otherwise. Furthermore, it’s impossible to predict *which* deleterious mutation will be the lucky one. But one thing from my work is clear: deleterious mutations do provide essential variation needed by evolving populations. 

Covert, Lenski, Wilke and Ofria (2013) Experiments on the role of deleterious mutations as stepping stones in adaptive evolution. PNAS doi: 10.1073/pnas.1313424110

 

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BEACON Researchers at Work: Effective Science Outreach

This week’s BEACON Researchers at Work post is by University of Texas at Austin graduate student Eben Gering.

What if, after years of work in the field or laboratory, every scientist had a chance to invite the public to dinner, and show them how discoveries are made? And what if the public came away from these events convinced that exciting and understandable research was being conducted by their neighbors, right in their own backyards? These are not hypothetical questions! Scientists, increasingly, are mandated to communicate our work with the public. If we get this right, we can ensure that the public remains informed about important issues affecting our health and environment, and understands the merits of basic research.

LOGO_by_VICKY_HUANGOne key challenge to effective outreach is that our professional training does not prepare us to communicate with non-scientific audiences. To help remedy this deficiency, the graduate students at The University of Texas at Austin formed Science Under the Stars in 2009. The program’s organizers have designed it to accomplish both outreach, and outreach training, simultaneously. The public gets to learn first hand about the exciting work being done by our speakers, while the organizers and speakers train ourselves in effective scientific outreach.  Over the course of 4+ years, we have learned a lot about producing successful outreach events. I would like to use this opportunity to share what makes Science Under the Stars work well, in hopes that some of it will be inspiring or useful to other scientists and educators.

1) Graduate students comprise a talented and tireless team. Our best resource has been the enthusiasm and diverse interests of integrative biology graduate students. Most of our speaker volunteers, and all of the organizers, came from this pool. For most of our speakers, the series provided a first opportunity to discuss their scientific interests with the public. Speakers were thus contagiously enthusiastic about their selected topics, and worked tirelessly to develop high quality presentations. For our organizers, the series offered a chance to develop and/or deploy skills of their choosing, from website development to creating educational activities. Our graphics, website, advertisements and programming were created by a dedicated and talented groups of organizers (whom you can meet on the program’s website).

LAURA_DUGAN_PHOTO_BY_IAN_WRIGHT2) Most scientists can benefit from coaching in outreach. One of the more important tasks undertaken by a subset of our organizers is preparing speakers to deliver accessible and engaging presentations. Academics are accustomed to giving hour-long technical presentations, and most of us require practice to avoid jargon while explaining scientific concepts. To keep talks accessible to non-scientists, Science Under the Stars organizers provided speakers with guidance and feedback on their selected themes and figures. We also quickly learned to keep presentations short (<30 minutes), and to allow plenty of time for questions. The audience invariably has questions, and is highly enthusiastic about interacting with speakers if sufficient time is given.

3) Location and atmosphere are important to the public. We were also strategic in selecting the venue for our events. Science Under the Stars is held outdoors (weather permitting) at The Brackenridge Laboratory of the University of Texas. This 80-acre field station lies in the heart of Austin. It provides both accessibility and a terrific ambience, complete with trees, butterfly-filled greenhouses, insect song and a fire pit.

3) Effective outreach doesn’t have to be expensive. In our first year, we ran Science Under the Stars on a shoestring budget, and borrowed most of our equipment from UT. With funding from BEACON (NSF) and Integrative Biology (UT), the program was later able to acquire dedicated equipment at the Brackenridge lab, including folding chairs, a PA system, and a large projection screen that makes for visually stunning presentations. Other items (e.g. our projector) were donated by UT’s College of Natural Sciences. Topics covered in past events range from an expedition to Antarctica to theoretical studies of pathogen evolution. At each event, organizers provide food, drink, and children’s activities themed around the topic of the evening. We have also held special events ad hoc including film competitions and field station tours. These low-cost activities have allowed us to keep our operating costs low as our audience grew in size.

My own involvement with Science Under the Stars concluded this spring, and was one of the most valuable and rewarding components of my graduate education. It left me with a strong drive to continue developing scientific outreach programs in the coming years. While I am not sure what form this will take, I think that programs resembling Science Under the Stars could be highly successful beyond Austin.

Over the years, Science Under the Stars began to accumulate a group of “regulars” of all ages and backgrounds. As our events were concluding, question and answer sessions often broadened into an open forum in which children, faculty, students and citizens traded thoughts, knowledge and questions about the topic of the evening.  It seemed to me that the organizers had, in these moments, created an effective and unusual form of outreach.

One of the things that sets the series apart is that it focuses on graduate student speakers, and thereby prepares young scientists to engage the public and media as opportunities arise. Another attractive feature of the format is that it engages adults as well children. By including adults in scientific outreach (which often targets only k-12 children) we can insure that today’s voters will make informed decisions, and instill enthusiasm for science in the home.

HAYLEY_GILLESPIE_PHOTO_BY_IAN_WRIGHT

To learn more about Science Under the Stars, including an overview of past talks and current and past organizers, please visit the program’s website (http://scienceunderthestars.org/). 

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BEACON Congress 2013: A social media summary

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Scientific Tweetability

Here at BEACON, we recently held our annual Congress, a conference where members from all five of our institutions come together to present research, network with each other, and brainstorm new ideas. One of the highlights of this year’s Congress was a talk by Titus Brown (@ctitusbrown on Twitter) about blogging and social media. Titus talked about how how these platforms work, gave some practical tips on how to proceed, and shared his experiences on how blogging and tweeting has affected his career as a professor, in both positive and negative ways. Notably, he’s drawn a lot of positive attention to himself and his work through social media – and this attention has attracted journalists, grant officers, and invited talks.

The talk inspired many BEACONites to open Twitter accounts and start blogs – including Rich Lenski, who has been blogging and tweeting prolifically ever since. (Seriously – follow him at @RELenski, and check out his blog, Telliamed Revisited!) 

Last week, I attended the annual NSF Science and Technology Centers Directors meeting. In case you don’t know already, BEACON is one of a handful of active Science and Technology Centers, or STCs. These centers are an innovative approach to scientific grand challenges, bringing together researchers from different fields and different institutions in a way that can’t usually be accomplished with typical, single-investigator grants. The theme of this year’s meeting was “Charting Today the Science & Technology of Tomorrow,” and a number of panelists were invited from the federal government, private corporations, and philanthropic organizations to present their views on the role that STCs could play in advancing science in the United States.

A prominent theme throughout the two days was effective science communication. This topic came up in nearly every session:

  • One of the first speakers was a member of the US House of Representatives, and in his opening remarks, he commented that he didn’t understand much of the science that we were doing, and he hoped that we would explain it to him. As requested, one of the first people who asked him a question tried to describe what his Center did in just a couple of sentences. Unfortunately, his “explanation” was full of jargon and buzzwords and it was clear to everyone that his explanation did nothing to clear things up for the congressman, who continued to frown uncomprehendingly during and after the explanation.
  • Later that day, a representative of a private grant foundation talked about the science that his foundation funds. He briefly presented one project, and stated that he was using this example “because it’s the only one I understand.”
  • Finally, several members of the National Science Board (NSB, the governing board for the NSF) talked about the importance of integrating the processes of science and policy-making. Scientists have a responsibility to provide continuous guidance to the federal government, but by the time the NSB is invited to comment on federal bills or policies, it is generally too late to change anything.

If you do good science, but nobody knows about it, does it matter?

Scientists are often portrayed as elitists and viewed with suspicion by some members of our society. Scientists who refuse to communicate in a way that others can understand are, in fact, elitists, who are actively excluding anyone who lacks their highly specific vocabulary. And they are hurting themselves by behaving this way. 

Communicating science effectively is not just about informing the public – which is important. It’s not just about getting K-12 students interested in science – which is also important. It is also about getting the support of decision-makers and funding sources – which is absolutely critical for the progress of science. 

Try it – try talking about your work to your non-scientist friends. Try getting it out into the world, in whatever way works for you. Social media is a great way to get started – it’s totally free and easy to use. Practice focusing on the “why” of your research – why do you study that particular problem, and why should anyone else care about it? The more you practice, the better you’ll be at communicating and the more the world will know and care about your work. And in the long term, your new communication abilities will help you get more grant money, more publicity, and more career advancement – and maybe even help make the world a better place.

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Meet BEACON's 2013 Distinguished Postdoctoral Fellow, Annat Haber

Annat Haber

Annat grew up in Israel, where she got both her B.Sc. and M.Sc. degrees. Her interest in vertebrate paleontology and macroevolution propelled her to move to the US for her PhD, which she received from the University of Chicago in 2010. 

Her academic interests have spanned a wide range of topics over the years. Her high school research project aimed to understand how feral cats that crowd the streets of Jerusalem manage to overcome their territorial and solitary nature as they aggregate around artificial food sources such as dumpsters. As an undergraduate student in Tel Aviv University, she was introduced to the world of comparative morphology and evolution while analyzing animal remains from a Neolithic site under the supervision of Tamar Dayan. This project has developed into her master’s thesis on the early stages of animal domestication. In order to better understand evolutionary processes in “deep time”, she moved to Dallas, TX, and studied marine adaptations in mosasaurs in collaboration with Louis Jacobs and Mike Polcyn. Her PhD work at the University of Chicago involved the morphometric analysis of the ruminant skull in more than 130 extant species, with the goal of studying the effect of morphological integration on their diversification patterns. 

Her future work at MSU will continue to explore the link between integration (character covariation within the population) and evolution. Understanding integration is crucial for understanding the evolutionary potential of species, because integration reflects the genetic and developmental factors that govern the coordinated development of different characters. These factors determine the kind of variation that is available for natural selection to work on: some combinations of characters would be more prevalent in the population than others because of their covariation, and therefore more amenable for selection. At the same time, integration itself evolves, and that could undermine its role in the evolution of the population: if the covariation structure can change quickly enough, so that any combination of characters is attainable when needed, then its potential to bias the evolution of the population will be limited. Both theoretical and empirical studies have shown that integration evolves in response to selection, mutational effects, and genetic drift, but the nature and consequences of this evolution is still poorly understood.

For her main project, Annat will be utilizing the experimental systems developed in the BEACON-associated laboratories of Ian Dworkin and Jeff Conner in order to better understand how integration evolves under different conditions. The mutant strains of Drosophila melanogaster developed in the Dworkin lab provide an opportunity to determine whether new mutations can fundamentally alter covariation, and if so, how. The selection experiments carried out by the Conner lab allow precise estimation of both selection and the genetic covariation, and thus a more thorough quantification of their interplay.

In addition to her experimental work, Annat is interested in using the Avida platform in order to extend her PhD study on the macroevolutionary implications of integration. Unlike natural systems, the model system of Avida combines easily-manipulated settings with organismal complexity that can be studied over time periods equivalent to geological time scales. This unique combination could provide unprecedented insights into what properties of integration affect evolution and diversification across different time scales and under different environmental regimes. These insights, along with the experimental results, could get us closer to understanding what makes complex systems evolvable while maintaining their robustness and functionality.

For more information about Annat’s work, you can contact her at annat22 at gmail dot com.

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